Bhavana Sunil Menkudale1*, Madhuri Pawar2
1Department of Rasa Shastra and Bhaishjya Kalpana, Bharati Vidyapeeth University, College of Ayurved, Pune 43, India.
2Department of Rasa Shastra and Bhaishjya Kalpana, Bharati Vidyapeeth University, College of Ayurved, Pune 43, India.
* Corresponding author
PG scholar, Department of Rasa Shastra and Bhaishajya Kalpana, Bharati Vidyapeeth University, College of Ayurveda, Pune 411043, India.
Abstract
Objective: Brahmi Ghrita (BG) is a medicated ghee formulation, comprises of Brahmi (Bacopa monnieri), Ela (Elettaria cardamomum) and Puran ghrita (10 years old cow ghee). It is recommended to treat broadly described mental illnesses especially in Unmad (Psychosis) and Apasmar (Epilepsy). However, Puran ghrita is not available in ample quantity and in current practice medicated ghee formulations are prepared with fresh go-ghrita (cow ghee). Though the potential of BG is having specific target action on brain tissue, thus to produce desired effect it should be prepared with certain standard operating procedures. Thus before initiating in vivo study, validation of manufacture process and laboratory analysis of Brahmi Ghrita prepared from Puran ghrita and fresh go-ghrita is essential. Materials and methods: In accordance to ayurvedic standard protocols, two samples of Brahmi ghrita were prepared with Puran Ghrita (BG I) and fresh cow ghee (BG II). Further validation and comparative physico-chemical analysis was done for both samples. Results: The physico-chemical parameters such as specific gravity, moisture content, acid value, iodine value, saponification value and peroxide value of BG I and BG II samples were almost alike. Conclusion: The process of manufacture and analytical values of BG I and BG II samples are validated and established in the study.
Keywords: Medicated ghee, Brahmi ghrita, Puran ghrita, fresh go-ghrita (cow ghee), Standardization
