Abdul Malek1, AbdurRazzak Mia2, ShyamSundar Shaha3, Abul Kalam Azad4*
1,3Department of Biochemistry, GonoshahsthayaSamajVittik Medical College, Dhaka, Bangladesh.
2Department of Biochemistry, Mymensingh medical College, Mymensingh, Bangladesh.
4Department of Basic Medical Sciences, Faculty of Pharmacy, International Islamic University Malaysia, Malaysia.
Corresponding Author
Md Abul Kalam Azad,
Department of Basic Medical Sciences,
Faculty of Pharmacy, International Islamic University Malaysia,
Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia.
Tel: 5704871, Fax: 5706775.
Abstract
Objectives: Aim of this study was to investigate and evaluate the Zinc and Magnesium levelsof serum among the Type 2 diabetes patients who have admitted in Mymensingh medical College, Bangladesh. Materials and methods:The study was designed to evaluate the serum Zn, Mg, Cu, Fe and Ca status in type2 diabetes mellitus patients. The subjects were selected on the basis of inclusion and exclusion criteria by purposive (non-random) method. This study included 60 type2 diabetic subjects as case. Results:The results were compared with 60 apparently healthy non diabetic subjects as control. Serum Zn, Mg, Cu, Fe and Ca levels were analyzed. All statistical analysis was done by using SPSS windows package. The values were expressed as Mean ± SD. Statistical significance of difference between two groups were evaluated by using student’s unpaired t-test. Serum zinc and magnesium were estimated by Atomic absorption spectrophotometry. The serum zinc and magnesium levels were (85.28±28.68 µ gm/dl) and (1.35±0.40 mg/dl) respectively in group I and (115.68±46.99 µ gm/dl) and (2.03±0.36 mg/dl) respectively in group II. The levels were significantly decreased in group I. Conclusion: outcome of this study showed that type 2 diabetes mellitus can result in changes in zinc and magnesium levels and supplementation of both zinc and magnesium may be considered in those cases.
Keywords: Zinc, magnesium, Type 2 Diabetes Mellitus
