Ajay Shukla*1, Sweta Garg2, Ashish Garg3, Vishal Singh3
1Department of Pharmaceutical Science, Mohanlal Sukhadia University, Udaipur Rajasthan, India
2Departmet of Pharmaceutical Chemistry, Guru Ramdas Khalsa Institute of Science & Technology Pharmacy, Jabalpur, India
3Department of Pharmaceutical Science, Guru Ramdas Khalsa Institute of Science & Technology Pharmacy, Jabalpur, India
*Address for Corresponding Author:
Mr. Ajay shukla
Department of Pharmaceutical Science,
Mohanlal Sukhadia University,
Udaipur Rajasthan, India
Abstract
Objective: Asthma in chronic condition is very tedious to cure and which is very common disease. The aim of study was to evaluate anti-asthmatic activity the ethanol extract of aerial part of A. aspera. Material and methods: Collection of Aerial parts of Achyranthes aspera is done from Bhopal. For authentication of aerial parts of A. aspera Herbarium of plant was made and sent to botany department of Safia College, Bhopal. The collected material was proceeded for air dry at 35-40º C and then it was pulverized in electric grinder. Extraction of obtained powder was completed in ethanol by using Soxhlet Apparatus. 8.45% w/w yield of substance was found. The presence of flavonides, phenolic compound, glycosides, tannins, saponins, alkaloids and carbohydrates were revealed by phytochemical screening. Ethanol extract of aerial part of A. aspera was performed for the screening of anti-asthmatic activity. Results and conclusion: The current study of the ethanol extract of aerial part of A. aspera was performed for the screening of anti-asthmatic activity of drug. The ethanol extract of aerial part of A. aspera was result the right side shift of dose response curve in isolated goat chain and isolated guinea pig so it is indicating antiasthmatic action of drug extract.
Keywords: Asthma, Achyranthes aspera, extract, phytochemical screening
